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Clinical data
Pronunciation/ ˌ ɛ s oʊ ˈ m ɛ p r ə ˌ z oʊ l, - ˈ m iː -, - ˌ z ɒ l / [2]
Trade namesNexium, others [1]
License dataEU  EMA:  by INN, US   FDA: Esomeprazole
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, IV
Drug classproton pump inhibitor
ATC codeA02BC05 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability50 to 90%
MetabolismLiver (CYP2C19, CYP3A4)
Elimination half-life1–1.5 hours
Excretion80% Kidney 20% Faecal

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Someprazole is a proton pump inhibitor that decreases the amount nexium 42 acid produced in the stomach.There is currently no generic form of Nexium. Prilosec is a mixture of R and S enantiomers of omeprazole.

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Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers. EXIUM is supplied as delayed-release capsules for oral administration or in nexium 24hr 42 eas for preparation of delayed-release oral suspensions.It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.

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Avoid concomitant use of rilpivirine or nelfinavir nexium 24hr 42 capsule NEXIUM Monitor INR and prothrombin time in patients treated with warfarin and NEXIUM, as increases in INR and prothrombin times have been seen NEXIUM may impact systemic exposure of CYP2C19 substrates eg, citalopram, cilostazol, digoxin, Esomeprazole may interfere with the absorption of drugs for which gastric pH affects bioavailability eg, erlotinib, dasatinib, nilotinib, ketoconazole, itraconazole, mycophenolate mofetil, and nexium 24hr 42 capsule salts Use NEXIUM with caution in transplant patients receiving mycophenolate mofetil NEXIUM may potentially increase exposure of tacrolimus.Inactive ingredients in NEXIUM Delayed-Release Capsules including the capsule shells glyceryl monostearate 40-55, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer type C, polysorbate 80, sugar nexium 24hr 42 capsules, talc, triethyl citrate, gelatin, FD C Blue #1, FD C Red #40, D C Red #28, titanium dioxide, shellac, ethyl alcohol, isopropyl alcohol, n-butyl alcohol, propylene glycol, sodium hydroxide, polyvinyl pyrrolidone, and D C Yellow #10.

Inactive granules in NEXIUM For Delayed-Release Oral Suspension: dextrose, xanthan gum, crospovidone, citric acid, iron oxide, and hydroxypropyl cellulose.

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Why take nexium an hour before meal?

R.Most patients improve with discontinuation of the PPI alone in 4 to 12 weeks Avoid concomitant use of NEXIUM with clopidogrel, due to a reduction in plasma concentrations of the active metabolite of clopidogrel.

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Worse, once a patient is on one of these who attempt to get off of PPIs are successful.The New York Times. May. Retrieved May. "Her Darkest Role: Actress Allison Mack's Descent From 'Smallville' to Sex Cult".

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