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Esomeprazole
Clinical data
Pronunciation/ ˌ ɛ s oʊ ˈ m ɛ p r ə ˌ z oʊ l, - ˈ m iː -, - ˌ z ɒ l / [2]
Trade namesNexium, others [1]
AHFS/Drugs.comMonograph
MedlinePlusa699054
License dataEU  EMA:  by INN, US   FDA: Esomeprazole
Pregnancy categoryAU: B3 US: C (Risk not ruled out)
Routes of administrationBy mouth, IV
Drug classproton pump inhibitor
ATC codeA02BC05 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability50 to 90%
MetabolismLiver (CYP2C19, CYP3A4)
Elimination half-life1–1.5 hours
Excretion80% Kidney 20% Faecal

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Someprazole is a proton pump inhibitor that decreases the amount nexium 42 acid produced in the stomach.There is currently no generic form of Nexium. Prilosec is a mixture of R and S enantiomers of omeprazole.

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Data sources include IBM Watson Micromedex updated 10 Aug 2020 Cerner Multum updated 3 Aug 2020 Wolters Kluwer updated 10 Aug 2020 andothers. EXIUM is supplied as delayed-release capsules for oral administration or in nexium 24hr 42 eas for preparation of delayed-release oral suspensions.It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.

This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus.

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Avoid concomitant use of rilpivirine or nelfinavir nexium 24hr 42 capsule NEXIUM Monitor INR and prothrombin time in patients treated with warfarin and NEXIUM, as increases in INR and prothrombin times have been seen NEXIUM may impact systemic exposure of CYP2C19 substrates eg, citalopram, cilostazol, digoxin, Esomeprazole may interfere with the absorption of drugs for which gastric pH affects bioavailability eg, erlotinib, dasatinib, nilotinib, ketoconazole, itraconazole, mycophenolate mofetil, and nexium 24hr 42 capsule salts Use NEXIUM with caution in transplant patients receiving mycophenolate mofetil NEXIUM may potentially increase exposure of tacrolimus.Inactive ingredients in NEXIUM Delayed-Release Capsules including the capsule shells glyceryl monostearate 40-55, hydroxypropyl cellulose, hypromellose, magnesium stearate, methacrylic acid copolymer type C, polysorbate 80, sugar nexium 24hr 42 capsules, talc, triethyl citrate, gelatin, FD C Blue #1, FD C Red #40, D C Red #28, titanium dioxide, shellac, ethyl alcohol, isopropyl alcohol, n-butyl alcohol, propylene glycol, sodium hydroxide, polyvinyl pyrrolidone, and D C Yellow #10.

Inactive granules in NEXIUM For Delayed-Release Oral Suspension: dextrose, xanthan gum, crospovidone, citric acid, iron oxide, and hydroxypropyl cellulose.

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CYP2C19 is an enzyme in the nexium 24hr 42 capsule that is responsible for breaking down esomeprazole and other drugs in the body. Some patients have less of this protein in their bodies, affecting how much of the drug gets eliminated.the content you have visited beforeAdvertising: Gather personally identifiable nexium 24hr 42 capsule such as name and location Essential: Remember your cookie permission settingEssential: Allow session cookiesEssential: Gather information you input into a contact forms, newsletter and other forms across all pagesEssential: Keep track of what you input in a shopping cartEssential: Authenticate that you are logged into your user accountEssential: Remember language version you selectedFunctionality: Remember social media settingsFunctionality: Remember selected region and country Remember your login detailsAnalytics: Keep track of your visited pages and interaction takenAnalytics: Keep track about your location and region based on your IP numberAnalytics: Keep track of the time spent on each pageAnalytics: Increase the data quality of the statistics functionsAdvertising: Tailor information and advertising to your interests based on e.

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R.Most patients improve with discontinuation of the PPI alone in 4 to 12 weeks Avoid concomitant use of NEXIUM with clopidogrel, due to a reduction in plasma concentrations of the active metabolite of clopidogrel.

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Worse, once a patient is on one of these who attempt to get off of PPIs are successful.The New York Times. May. Retrieved May. "Her Darkest Role: Actress Allison Mack's Descent From 'Smallville' to Sex Cult".

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