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2004 Dec. Epub 2004 Nov 24. ubMed: 5564772Cieslewicz G, Gondorowicz K, Grzelewska-Rzymowska I, Rozniecki J: ffect of loratadine, desloratadine interaction professor of desloratadine interaction H1 receptors, on cheap-induced bronchoconstriction.

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E-mail address, name, etc.Lethality occurred in rats at oral doses of 250 mg/kg or greater estimated desloratadine and desloratadine metabolite exposures were approximately 120 times the AUC in humans at the recommended daily oral dose The desloratadine brand name usa median lethal dose in mice was 353 mg/kg estimated desloratadine exposures were approximately 290 times the human daily oral dose on a mg/m2 basis No deaths occurred at oral doses up to 250 mg/kg in monkeys estimated desloratadine exposures were approximately 810 times the human daily oral dose on a mg/m2 basis In adult patients with liver or renal impairment, a starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.

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