IV ozone therapy refers to the process of administering ozone gas into the bloodstream to stimulate the immune system and treat disease and pathogens. IV ozone therapy can be used in a multitude of ways as a powerful healer, as it helps to increase mitochondrial cellular energy production. Ozone (O3) stimulates the uptake of oxygen so that it can be used by cells in the body. When your cells receive a flood of oxygen, they function more optimally—helping your body fight and prevent disease and other variants that cause illness.